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[1]黄和,任路静,魏萍,等.生物素和浅蓝菌素添加对裂殖壶菌发酵产DHA的影响[J].生物加工过程,2012,10(01):42-45.[doi:10.3969/j.issn.1672-3678.2012.01.008]
 REN Lujing,WEI Ping,FENG Yun,et al.Effect of biotin and cerulenin addition on DHA production by Schizochytrium sp.[J].Chinese Journal of Bioprocess Engineering,2012,10(01):42-45.[doi:10.3969/j.issn.1672-3678.2012.01.008]
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生物素和浅蓝菌素添加对裂殖壶菌发酵产DHA的影响()
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《生物加工过程》[ISSN:1672-3678/CN:32-1706/Q]

卷:
10
期数:
2012年01期
页码:
42-45
栏目:
出版日期:
2012-01-30

文章信息/Info

Title:
Effect of biotin and cerulenin addition on DHA production by Schizochytrium sp.
文章编号:
1672-3678(2012)01-0042-04
作者:
黄和任路静魏萍冯云纪晓俊
南京工业大学生物与制药工程学院,南京210009
Author(s):
REN LujingWEI PingFENG YunJI XiaojunHUANG He
College of Biotechnology and Pharmaceutical Engineering, Nanjing University of Technology, Nanjing 210009, China
关键词:
生物素浅蓝菌素裂殖壶菌DHA
分类号:
Q815
DOI:
10.3969/j.issn.1672-3678.2012.01.008
文献标志码:
A
摘要:
为提高发酵产量,根据裂殖壶菌生物合成二十二碳六烯酸(DHA)的途径,考察添加代谢途径关键酶的辅酶及酶的抑制剂对发酵裂殖壶菌的影响。结果表明:添加生物素可促进油脂积累,添加浅蓝菌素有利于DHA及不饱和脂肪酸含量的提高。添加生物素03 mg/L时,DHA占细胞干质量分数达1126%,相对于对照提高了13%;当添加浅蓝菌素01mg/L时,DHA占细胞干质量分数可达122%。

参考文献/References:

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备注/Memo

备注/Memo:
江苏省高校产业化推进项目(JH0930);江苏省六大高峰人才项目(2008D63);教育部新世纪优秀人才支持计划资助项目(NCET090157);霍英东教育基金资助项目(123014)
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